| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Hibernians | 27 | 15 | 9 | 3 | 46 | 23 | +23 | 54 | LWWDL |
| 2 | Floriana | 27 | 14 | 9 | 4 | 38 | 21 | +17 | 51 | WDDDL |
| 3 | Hamrun Spartans | 27 | 13 | 6 | 8 | 33 | 24 | +9 | 45 | WDWLW |
| 4 | Gzira United | 27 | 12 | 7 | 8 | 46 | 38 | +8 | 43 | WWLDW |
| 5 | Birkirkara | 27 | 10 | 11 | 6 | 35 | 27 | +8 | 41 | LLDDW |
| 6 | Gudja United | 27 | 10 | 2 | 15 | 29 | 35 | -6 | 32 | LLLWL |
| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Hibernians | 22 | 13 | 8 | 1 | 39 | 18 | +21 | 47 | WWDLW |
| 2 | Floriana | 22 | 13 | 6 | 3 | 36 | 19 | +17 | 45 | LWWWW |
| 3 | Birkirkara | 22 | 9 | 9 | 4 | 30 | 22 | +8 | 36 | DDLWD |
| 4 | Hamrun Spartans | 22 | 10 | 5 | 7 | 28 | 22 | +6 | 35 | WWDDL |
| 5 | Gzira United | 22 | 9 | 6 | 7 | 39 | 33 | +6 | 33 | WWLLW |
| 6 | Gudja United | 22 | 9 | 2 | 11 | 26 | 25 | +1 | 29 | WLLWW |
| 7 | Sirens | 22 | 7 | 6 | 9 | 28 | 38 | -10 | 27 | LLLDD |
| 8 | Valletta FC | 22 | 7 | 5 | 10 | 28 | 34 | -6 | 26 | DDWLL |
| 9 | Mosta | 22 | 6 | 7 | 9 | 32 | 41 | -9 | 25 | LDWWL |
| 10 | Balzan FC | 22 | 7 | 2 | 13 | 30 | 33 | -3 | 23 | LLWLL |
| 11 | Santa Lucía | 22 | 4 | 10 | 8 | 28 | 38 | -10 | 22 | WLWWD |
| 12 | Sliema Wanderers | 22 | 2 | 6 | 14 | 12 | 33 | -21 | 12 | LDLLD |
| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Valletta FC | 27 | 10 | 6 | 11 | 39 | 40 | -1 | 36 | WLDWW |
| 2 | Sirens | 27 | 9 | 7 | 11 | 40 | 48 | -8 | 34 | WLWDL |
| 3 | Mosta | 27 | 8 | 8 | 11 | 41 | 50 | -9 | 32 | LWDWL |
| 4 | Balzan FC | 27 | 9 | 3 | 15 | 37 | 42 | -5 | 30 | WWDLL |
| 5 | Santa Lucía | 27 | 5 | 12 | 10 | 36 | 45 | -9 | 27 | LLDDW |
| 6 | Sliema Wanderers | 27 | 4 | 6 | 17 | 16 | 43 | -27 | 18 | LWLLW |
Player stats
Maltese Premier League match stats only.
Santa Lucía were relegated in the Maltese Premier League in 2021/22, finishing 11th with 22 points (4W 10D 8L). They scored 28 and conceded 38, a goal difference of -10. Vito Plut top-scored with 8 goals. The final table, every result and the season's team statistics are below.