| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Akwa United | 38 | 19 | 14 | 5 | 53 | 24 | +29 | 71 | LWDWW |
| 2 | Enyimba | 38 | 18 | 12 | 8 | 41 | 33 | +8 | 66 | WDDWD |
| 3 | Kwara United | 38 | 19 | 8 | 11 | 48 | 28 | +20 | 65 | WWWDW |
| 4 | Nasarawa United | 38 | 20 | 5 | 13 | 55 | 38 | +17 | 65 | LWDWL |
| 5 | Kano Pillars | 38 | 19 | 7 | 12 | 38 | 29 | +9 | 64 | LWLWL |
| 6 | Rivers United | 38 | 18 | 9 | 11 | 48 | 36 | +12 | 63 | LWDWL |
| 7 | Enugu Rangers | 38 | 18 | 8 | 12 | 43 | 31 | +12 | 62 | WLWDW |
| 8 | Lobi Stars | 38 | 17 | 7 | 14 | 43 | 39 | +4 | 58 | WLDDW |
| 9 | Plateau United | 38 | 14 | 9 | 15 | 45 | 35 | +10 | 51 | LWLDL |
| 10 | MFM | 38 | 13 | 12 | 13 | 34 | 35 | -1 | 51 | WLWDL |
| 11 | Akwa Starlets | 38 | 15 | 5 | 18 | 37 | 47 | -10 | 50 | LLDLW |
| 12 | Katsina United | 38 | 14 | 7 | 17 | 35 | 42 | -7 | 49 | LWLWD |
| 13 | Heartland | 38 | 13 | 9 | 16 | 43 | 50 | -7 | 48 | WLLDL |
| 14 | Abia Warriors | 38 | 12 | 11 | 15 | 48 | 42 | +6 | 47 | WLWLW |
| 15 | Wikki Tourist | 38 | 12 | 9 | 17 | 40 | 47 | -7 | 45 | WLWLL |
| 16 | Sunshine Stars | 38 | 11 | 12 | 15 | 28 | 39 | -11 | 45 | WDWLD |
| 17 | Jigawa Golden Stars | 38 | 11 | 10 | 17 | 29 | 46 | -17 | 43 | LWDLW |
| 18 | Warri Wolves | 38 | 11 | 8 | 19 | 30 | 45 | -15 | 41 | LWDWL |
| 19 | Ifeanyi Uba | 38 | 9 | 12 | 17 | 33 | 50 | -17 | 39 | WLLDL |
| 20 | Adamawa United | 38 | 5 | 10 | 23 | 20 | 55 | -35 | 25 | LLLDL |
Jigawa Golden Stars were relegated in the NPFL in 2021/22, finishing 17th with 43 points (11W 10D 17L). They scored 29 and conceded 46, a goal difference of -17. The final table, every result and the season's team statistics are below.
