| # | Team | P | W | D | L | GF | GA | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Zenit | 30 | 19 | 8 | 3 | 76 | 26 | +50 | 65 | WDWWD |
| 2 | Spartak Moscow | 30 | 17 | 6 | 7 | 56 | 37 | +19 | 57 | DWWWL |
| 3 | Lokomotiv | 30 | 17 | 5 | 8 | 45 | 35 | +10 | 56 | WDLWW |
| 4 | Rubin | 30 | 16 | 5 | 9 | 42 | 33 | +9 | 53 | DWWLW |
| 5 | PFC Sochi | 30 | 15 | 8 | 7 | 49 | 33 | +16 | 53 | DWWWW |
| 6 | CSKA Moscow | 30 | 15 | 5 | 10 | 51 | 33 | +18 | 50 | LWDLL |
| 7 | Dynamo | 30 | 15 | 5 | 10 | 44 | 33 | +11 | 50 | WDLLW |
| 8 | Khimki | 30 | 13 | 6 | 11 | 35 | 39 | -4 | 45 | DLWWL |
| 9 | FC Rostov | 30 | 13 | 4 | 13 | 37 | 35 | +2 | 43 | LLWWL |
| 10 | FC Krasnodar | 30 | 12 | 5 | 13 | 52 | 45 | +7 | 41 | WLLWD |
| 11 | Akhmat | 30 | 11 | 7 | 12 | 36 | 38 | -2 | 40 | DWLDW |
| 12 | Ural | 30 | 7 | 13 | 10 | 26 | 36 | -10 | 34 | LWLDL |
| 13 | FC UFA | 30 | 6 | 7 | 17 | 26 | 46 | -20 | 25 | WDDLW |
| 14 | Arsenal Tula | 30 | 6 | 5 | 19 | 28 | 51 | -23 | 23 | LLLLW |
| 15 | Rotor Volgograd | 30 | 5 | 7 | 18 | 15 | 52 | -37 | 22 | DLWLL |
| 16 | Tambov | 30 | 3 | 4 | 23 | 19 | 65 | -46 | 13 | LLLLL |
Player stats
Russian Premier League match stats only.
FC Rostov finished 9th in the Russian Premier League in 2020/21 with 43 points (13W 4D 13L). They scored 37 and conceded 35, a goal difference of +2. Kento Hashimoto and Dmitri Poloz top-scored with 6 each and Dmitri Poloz led the assists with 3 assists. The final table, every result and the season's team statistics are below.
